What is pinned aminos?

Pinned aminos refer to amino acids that are covalently linked to a solid support matrix, such as polyethylene glycol. This immobilization technology is used in peptide synthesis, drug discovery, and proteomics research. Pinned amino acids allow for more efficient purification and isolation of peptides, as well as the construction of more complex protein structures. Additionally, this technology enables the creation of stable peptide and protein arrays for high-throughput screening and analysis.